Aromatase and gynecomastia

G D Braunstein

Department of Medicine, Cedars-Sinai Medical Center, UCLA School of Medicine, Los Angeles, California, USA

(Requests for offprints should be addressed to G D Braunstein, Room B-118, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, California 90048, USA)

Introduction

Gynecomastia, which represents a benign proliferation of the breast glandular tissue, can be detected in up to 70% of boys during puberty and between one-third and two-thirds of adults (Braunstein 1993). This common clinical condition results from an imbalance in estrogen action relative to androgen action at the breast tissue level.

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Endocrine-Related Cancer

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